Transmission of metastatic glioblastoma multiforme from donor to lung transplant recipient.
Level 4 - case-series / case-control
Single case report and narrative literature review
PubMed 18520546 · doi:10.1097/RCT.0b013e318076b472
What was done
The authors report a single clinical case of a lung transplant recipient presenting with lung masses evaluated by diagnostic workup and biopsy, along with a narrative review of similar cases from the literature.
What was found
The lung masses were determined on biopsy to be metastatic glioblastoma multiforme acquired from the lung donor. The abstract provides no numerical data, case counts from the literature review, or specific clinical measurements.
Why it matters
This case demonstrates the rare potential for primary central nervous system malignancies, specifically glioblastoma multiforme, to be transmitted from an organ donor to a solid organ transplant recipient.
Limits
As a single-patient case report with an unspecified narrative review, the findings cannot establish transmission rates or broader clinical risks. The abstract does not report details regarding donor history, patient follow-up, clinical outcomes, or the methodology of the literature review.
Cited by
- supports Organ transplants from donors with glioblastoma multiforme have transmitted metastatic cancer to the transplant recipients.