Burklund · Frontiers in psychology 2014 · Within-subjects experimental neuroimaging study · n=39

The common and distinct neural bases of affect labeling and reappraisal in healthy adults.

Level 4 - case-series / case-control

Cross-sectional within-subjects laboratory neuroimaging experiment

PubMed 24715880 · doi:10.3389/fpsyg.2014.00221 · record verified 2026-08-26

What was done

Thirty-nine healthy older adults (N = 39) completed a laboratory neuroimaging task comparing incidental emotion regulation (affect labeling) and intentional emotion regulation (cognitive reappraisal) against an observe-only control condition while viewing aversive images. Researchers evaluated prefrontal and amygdala neural responses alongside self-reported distress ratings.

What was found

The abstract does not provide exact numerical values, effect sizes, or confidence intervals. Qualitatively, both affect labeling and reappraisal activated shared prefrontal regulatory regions, with direct comparisons indicating stronger prefrontal responses during affect labeling. Both strategies demonstrated similar reductions in amygdala activity relative to the control condition and produced correlated reductions in self-reported distress.

Why it matters

The findings show that incidental emotion modulation via simple verbal labeling recruits overlapping prefrontal-amygdala circuitry and yields experiential relief comparable to effortful, deliberate cognitive reappraisal.

Limits

The study is limited by a modest sample size (N = 39) restricted exclusively to healthy older adults, which may not generalize to younger demographics or clinical populations with affective disorders. The abstract provides no exact quantitative metrics or statistical test values, and real-world durability of emotion modulation was not assessed.