Targeting the gut microbiota by dietary nutrients: A new avenue for human health.
Level 5 - mechanism / opinion, no new human data
Narrative review synthesizing mechanistic relationships without systematic review methodology or primary human data.
PubMed 28846450 · doi:10.1080/10408398.2017.1363708
What was done
This narrative review summarizes literature examining the interrelationships among dietary macronutrients and micronutrients, gut microbiota composition, microbial metabolite production, and host physiological systems.
What was found
The abstract outlines mechanistic pathways linking diet-derived microbial metabolites to host metabolic, immune, neural, and endocrine regulation, but reports no quantitative empirical data or effect sizes.
Why it matters
It maps potential mechanistic pathways by which dietary modification might be leveraged to alter microbial metabolism and influence host health.
Limits
As a non-systematic narrative review, it lacks formal study selection criteria, risk-of-bias assessment, and direct clinical outcome data. No quantitative human trial results are reported.
Cited by
- supports The gut microbiome consists of trillions of microorganisms in the digestive tract that influence immune function, metabolic health, and hormone levels.