Gosain · World journal of surgery 2004 · narrative review · n=?

Aging and wound healing.

Cited 1042 times in the scientific literature.

Level 5 - mechanism / opinion, no new human data

Narrative review with no systematic search methodology or original data reported

PubMed 14961191 · doi:10.1007/s00268-003-7397-6 · record verified 2026-08-26

What was done

This is a narrative review summarizing age-related physiological changes in normal skin and the mechanistic alterations that influence wound repair in older individuals.

What was found

The abstract reports no numerical data, statistics, or effect sizes. It states that consensus views aging as causing a delay in wound healing rather than an intrinsically defective repair, with the final outcome being qualitatively similar to that seen in younger individuals.

Why it matters

It contextualizes age-related wound repair deficits as a kinetic delay rather than an inability to achieve adequate tissue restoration.

Limits

The abstract provides no empirical data, sample size, or systematic methodology. Specific wound types, timelines, clinical variables, and molecular mechanisms are not detailed.

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