Aron · Journal of neurophysiology 2005 · within-subject fMRI study · n=17

Reward, motivation, and emotion systems associated with early-stage intense romantic love.

Cited 972 times in the scientific literature.

Level 4 - case-series / case-control

Cross-sectional within-subject neuroimaging study (design analogy for non-clinical neuroscience)

PubMed 15928068 · doi:10.1152/jn.00838.2004 · record verified 2026-08-26

What was done

Researchers conducted functional magnetic resonance imaging (fMRI) on 17 participants (10 women and 7 men) reporting early-stage intense romantic love (duration 1 to 17 months). Participants alternated between viewing a photograph of their romantic partner and a photograph of a familiar acquaintance, separated by an attention-distraction task, to isolate neural responses specific to their beloved.

What was found

The abstract reports directional activations and correlations without exact statistical values or effect sizes. Specific activation when viewing the beloved occurred in dopamine-rich reward areas: the right ventral tegmental area (VTA) and the right postero-dorsal body and medial caudate nucleus. Activation in the left VTA correlated with facial attractiveness ratings, right anteromedial caudate activation correlated with survey-assessed romantic passion intensity, and left insula-putamen-globus pallidus activation correlated with trait affect intensity.

Why it matters

This study provides evidence that early-stage romantic love engages basic subcortical mammalian reward and motivation circuits rather than solely higher-order emotional systems, helping explain the focused drive toward a preferred partner.

Limits

The study is limited by a very small sample size (n = 17) and cross-sectional correlational imaging, which cannot establish causality. The abstract does not provide exact effect sizes, test statistics, or p-values, and the duration of romantic love varied widely from 1 to 17 months.

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