Byrne · Psychophysiology 1992 · within-subject experimental physiological study · n=71

Frequency-specific amplification of heart rate rhythms using oscillatory tilt.

Cited 17 times in the scientific literature.

Level 4 - case-series / case-control

Uncontrolled within-subject laboratory physiological experiment in healthy volunteers

PubMed 1609023 · doi:10.1111/j.1469-8986.1992.tb02022.x · record verified 2026-08-28

What was done

Seventy-one healthy adults (36 male, 35 female, aged 18–30 years) were positioned on a tilt-table and oscillated at 0.08 Hz with a maximum tilt angle of +21 degrees for a 10-minute period. Heart period, heart period variability at 0.08 Hz (Traube-Hering-Mayer [THM] variance), and respiratory sinus arrhythmia (quantified as vagal tone, V) were measured. In a subset of 21 subjects, continuous measures and respiratory activity were analyzed at the onset of tilt.

What was found

The abstract reports statistical directions without exact numeric values. Oscillatory tilt significantly increased the amplitude of 0.08 Hz THM variance, while heart period, vagal tone, and respiration frequency did not change significantly during stimulation. After tilt cessation, THM variance returned to baseline, heart period lengthened in males, and vagal tone increased in both sexes. Higher baseline vagal tone was associated with a more rapid THM variance response to tilt onset.

Why it matters

The study shows that low-frequency mechanical oscillation can selectively drive specific baroreflex-mediated heart rate rhythms without disrupting baseline heart rate or respiration, providing a method to test psychophysiological hypotheses.

Limits

The abstract provides no quantitative data, effect sizes, or confidence intervals. The design was an uncontrolled, single-group laboratory intervention without a sham condition, limited to healthy young adults aged 18–30.

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