Sharot · Proceedings of the National Academy of Sciences of the United States of America 2007 · cross-sectional observational neuroimaging study · n=?

How personal experience modulates the neural circuitry of memories of September 11.

Cited 199 times in the scientific literature.

Level 4 - case-series / case-control

Cross-sectional observational neuroimaging study comparing two naturalistic exposure groups

PubMed 17182739 · doi:10.1073/pnas.0609230103 · record verified 2026-08-26

What was done

Three years after the September 11, 2001 terrorist attacks in New York City, researchers assessed behavioral recall and functional brain imaging in participants who were in Downtown Manhattan (close to the World Trade Center) versus Midtown (a few miles away) during the attacks. Participants retrieved memories of 9/11 as well as personally selected control events from 2001 while undergoing brain imaging.

What was found

Participants who were Downtown during the attacks exhibited selective amygdala activation and reported emotionally enhanced recollective experiences when recalling 9/11 compared to control events. In contrast, Midtown participants did not show selective amygdala activation or enhanced recollective experiences. The abstract reports no quantitative values, effect sizes, or participant counts.

Why it matters

These findings suggest that physical proximity and direct personal exposure during a traumatic event are critical for engaging the amygdala-dependent neural circuitry that characterizes vivid, emotionally enhanced "flashbulb" memories.

Limits

The abstract does not state the sample size, demographic characteristics, or quantitative statistical values. The study relies on retrospective recall three years post-event and an observational, non-randomized grouping based on naturalistic geographic exposure.

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