Rhoades Lecture. Effect of infection on nutrient requirements.
Level 5 - mechanism / opinion, no new human data
Narrative review/lecture presenting mechanism-based reasoning without primary empirical data or systematic synthesis.
PubMed 1766046 · doi:10.1177/0148607191015006589
What was done
Narrative lecture summarizing the physiological mechanisms and clinical consequences of infection on nutrient intake, absorption, metabolic expenditure, and recovery, particularly in hospitalized patients.
What was found
The abstract reports no numerical data. Qualitatively, it states that infections—including mild and subclinical cases—decrease nutrient intake and increase nutrient losses via reduced intestinal absorption, direct gastrointestinal losses, metabolic diversion, and increased basal metabolic rate during fever, affecting protein, energy, and micronutrient status.
Why it matters
Synthesizes the mechanisms linking infection to worsened nutritional status, highlighting the importance of nutritional support during illness and convalescence in vulnerable hospitalized patients.
Limits
Narrative review containing no primary empirical data, no sample size or systematic search strategy, and no quantitative statistical outcomes.
Cited by
- supports The body's metabolic rate increases and burns more energy during an active infection and immune response.