Yoo · Current biology : CB 2007

The human emotional brain without sleep--a prefrontal amygdala disconnect.

Cited 1313 times in the scientific literature.

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PubMed 17956744 · doi:10.1016/j.cub.2007.08.007 · record verified 2026-08-31

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• supports In a 2007 MRI study, the amygdala was 60% more reactive to negative and aversive images in sleep-deprived participants compared to well-rested controls.in Dr. Matthew Walker on Sleep for Enhancing Learning, Creativity, Immunity, and Glymphatic System
• supports Sleep deprivation shuts down top-down inhibitory connectivity from the prefrontal cortex to the amygdala.in Dr. Matthew Walker on Sleep for Enhancing Learning, Creativity, Immunity, and Glymphatic System