Merchant · Clinical orthopaedics and related research 2008 · systematic review · n=?

The female knee: anatomic variations and the female-specific total knee design.

Cited 122 times in the scientific literature.

Level 4 - case-series / case-control

Systematic review of predominantly observational and anatomical studies (graded as Level IV by the journal)

PubMed 18820981 · doi:10.1007/s11999-008-0536-5 · record verified 2026-08-26

What was done

The authors reviewed peer-reviewed literature to assess whether women experience worse clinical outcomes than men following traditional total knee arthroplasty (TKA). They also evaluated the evidence supporting three proposed gender-based anatomical differences: an increased Q angle, less prominence of the anterior medial and lateral femoral condyles, and a reduced medial-lateral to anterior-posterior femoral condylar aspect ratio.

What was found

No quantitative data, effect sizes, or study counts are reported in the abstract. Directionally, the review found that women experience equal or better results compared to men after traditional TKA. Regarding anatomical claims, the authors determined that the first two proposed differences (increased Q angle and decreased anterior condylar prominence) do not exist, and the third (aspect ratio variation) is so small that it likely carries no clinical effect.

Why it matters

This paper challenges direct-to-consumer and industry claims regarding the necessity of gender-specific knee implants, indicating that traditional prostheses are suitable and effective for female patients.

Limits

The abstract provides no numerical data, sample sizes, or count of included studies. Specific search strategies, database sources, inclusion criteria, and formal risk-of-bias or quality assessments are not described in the abstract text.

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