Higgins · The American journal of psychiatry 1991 · Non-randomized comparative study · n=25

A behavioral approach to achieving initial cocaine abstinence.

Cited 560 times in the scientific literature.

Level 3 - non-randomized controlled study

Non-randomized comparative cohort study of consecutive admissions

PubMed 1883001 · doi:10.1176/ajp.148.9.1218 · record verified 2026-08-26

What was done

Consecutive outpatients admitted for cocaine dependence were non-randomly offered either a behavioral treatment program combining contingency management with the community reinforcement approach (n = 13 offered, 13 accepted) or 12-step counseling (n = 15 offered, 12 accepted). Treatment retention and continuous cocaine abstinence were tracked over 12 weeks.

What was found

Retention at 12 weeks was higher in the behavioral treatment group (11 of 13) than in the 12-step counseling group (5 of 12). Continuous abstinence rates favored behavioral treatment across all reported time points: 4 weeks was achieved by 10 of 13 behavioral patients versus 3 of 12 counseling patients; 8 weeks was achieved by 6 of 13 versus 0 of 12; and 12 weeks was achieved by 3 of 13 versus 0 of 12.

Why it matters

This study provides early comparative evidence that combining contingency management with the community reinforcement approach improves outpatient treatment retention and initial continuous abstinence for cocaine dependence over standard 12-step counseling.

Limits

The study was non-randomized and relied on sequentially admitted cohorts, introducing potential selection bias. The sample size was very small (total n = 25 accepted and treated), and outcomes beyond 12 weeks were not reported in the abstract.

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