Usatine · American family physician 2011 · narrative review · n=?

Diagnosis and treatment of lichen planus.

Cited 56 times in the scientific literature.

Level 5 - mechanism / opinion, no new human data

Narrative clinical review without systematic review methodology

PubMed 21766756 · record verified 2026-08-31

What was done

This is a narrative review summarizing the clinical features, diagnosis (clinical evaluation and 4-mm punch biopsy), and management options for cutaneous, mucosal, genital, scalp, and nail lichen planus.

What was found

The abstract reports no numerical data or quantitative outcomes. It identifies classic presentation via the six Ps (planar, purple, polygonal, pruritic, papules, plaques) and Wickham striae. High-potency topical corticosteroids represent first-line treatment for cutaneous, genital, and mucosal erosive forms. Topical tacrolimus is cited for vulvovaginal disease, systemic corticosteroids for severe widespread involvement, and acitretin or immunosuppressants for refractory cases. Lesions may resolve spontaneously within 1 to 2 years, though mucosal disease is noted to be more persistent.

Why it matters

It provides primary care clinicians with practical diagnostic criteria and a stepped-care management pathway for lichen planus.

Limits

As a narrative review, it presents expert guidance without systematic search criteria, meta-analytic pooling, sample sizes, or quantitative outcome measures.

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