Association of acanthosis nigricans and skin tags with insulin resistance.
Level 5 - mechanism / opinion, no new human data
Narrative review without systematic methodology or primary human data
PubMed 22481657 · doi:10.1590/s0365-05962012000100012
What was done
Narrative review examining the clinical association between insulin resistance and specific dermatologic manifestations, specifically acanthosis nigricans and acrochordons (skin tags).
What was found
The abstract reports no quantitative data, prevalence rates, effect sizes, or participant numbers. It descriptively notes an association between insulin resistance, acanthosis nigricans, and skin tags as potential markers for non-insulin-dependent diabetes.
Why it matters
Recognizing external dermatologic signs during routine physical examination may assist clinicians in identifying potential insulin resistance prior to advanced metabolic complications.
Limits
No primary empirical data, systematic search protocol, sample size, or diagnostic accuracy metrics (such as sensitivity or specificity) are provided in the abstract.
Cited by
- supports Acanthosis nigricans and skin tags are strong clinical physical indicators of insulin resistance.