Clinical features of delirious mania: a series of five cases and a brief literature review.
Level 4 - case-series / case-control
Case series of five patients with a selective narrative literature review
PubMed 22716018 · doi:10.1186/1471-244X-12-65
What was done
The authors described the clinical presentation and treatment response of five patients with delirious mania admitted to an acute inpatient psychiatric unit between January 2005 and January 2007, alongside a selective narrative review of the literature.
What was found
Two patients had two episodes of delirious mania. Delirium generally resolved faster than mania. Delirious mania remitted within seven sessions of electroconvulsive therapy (ECT) in all five cases. No other specific quantitative metrics or statistical comparisons were reported in the abstract.
Why it matters
Delirious mania remains an under-recognized, potentially life-threatening syndrome lacking formal classification. These cases suggest that electroconvulsive therapy can provide rapid remission and may help prevent prolonged hospitalization.
Limits
The evidence is limited to an uncontrolled case series of only five patients at a single institution with no control group, alongside a non-systematic literature review. Standardized outcome measures and long-term follow-up details were not reported in the abstract.
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