Westcott · Current sports medicine reports 2012 · narrative review · n=?

Resistance training is medicine: effects of strength training on health.

Cited 775 times in the scientific literature.

Level 5 - mechanism / opinion, no new human data

Narrative review synthesizing literature without systematic search methodology or meta-analytic data

PubMed 22777332 · doi:10.1249/JSR.0b013e31825dabb8 · record verified 2026-08-28

What was done

This paper is a narrative review synthesizing literature on the musculoskeletal, metabolic, cardiovascular, and functional health effects of resistance training in adults, specifically addressing consequences of physical inactivity and aging. Search methodology, study selection, and review protocols were not specified in the abstract.

What was found

Inactive adults experience a 3% to 8% loss of muscle mass per decade, accompanied by reduced resting metabolic rate (RMR) and fat accumulation. Ten weeks of resistance training was reported to increase lean mass by 1.4 kg, increase RMR by 7%, and reduce fat mass by 1.8 kg. Bone mineral density was reported to increase by 1% to 3%. The abstract also reports improvements in physical performance, movement control, walking speed, functional independence, cognitive abilities, self-esteem, glycemic markers (decreased visceral fat, reduced HbA1c, increased GLUT4 density, improved insulin sensitivity), lipid profiles (decreased LDL-C and triglycerides, increased HDL-C), resting blood pressure, and symptom severity in low back pain, arthritis, and fibromyalgia.

Why it matters

This review aggregates evidence supporting resistance training as a clinical intervention to counter sarcopenia and improve multiorgan metabolic and cardiovascular risk factors in adults.

Limits

The abstract describes a narrative review without reporting the number of included studies, total sample sizes, search methodology, or risk of bias assessments. No confidence intervals, variance measures, or statistical significance metrics are provided for the cited numerical estimates.

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