Postmenopausal skin and estrogen.
Level 5 - mechanism / opinion, no new human data
Narrative review without systematic search or meta-analytic methodology.
PubMed 22849791 · doi:10.3109/09513590.2012.705392
What was done
This narrative review summarizes literature regarding the presence of estrogen receptors in skin cells and evaluates the potential of systemic and topical estrogen replacement therapies to mitigate postmenopausal skin aging and enhance wound healing.
What was found
The abstract provides no quantitative data, effect sizes, or statistical metrics. It qualitatively reports that both systemic and topical estrogen treatments appear to increase skin collagen content, thickness, elasticity, and hydration, while potentially improving wound healing and reducing wound complications.
Why it matters
It synthesizes the physiological rationale and clinical observations supporting estrogen's role in maintaining skin structure and function after menopause.
Limits
The abstract describes a non-systematic narrative review without specified study selection criteria, sample sizes, or quantitative data. It does not report treatment dosages, routes of administration, duration, or systemic safety risks associated with estrogen therapies.
Cited by
- supports Hormone replacement therapy helps mitigate and reduce postmenopausal skin collagen loss.