Buzalaf · Journal of applied oral science : revista FOB 2012 · literature review · n=?

Saliva and dental erosion.

Cited 422 times in the scientific literature.

Level 5 - mechanism / opinion, no new human data

Narrative literature review focusing on biological and physiological mechanisms without meta-analysis

PubMed 23138733 · doi:10.1590/s1678-77572012000500001 · record verified 2026-08-28

What was done

The authors conducted a search on MEDLINE for papers published from 1969 to 2010 examining the role of salivary factors in the development of dental erosion. Search terms included "saliva", "acquired pellicle", "salivary flow", "salivary buffering capacity", and "dental erosion". Study inclusion, data extraction, and quality assessment were performed independently and in duplicate by two reviewers, with disagreements resolved by consensus or a third reviewer.

What was found

No quantitative findings, sample sizes, or effect estimates were reported in the abstract. Qualitatively, salivary factors protect against erosion through acid clearance via swallowing, acid dilution via flow, neutralization via buffering capacity, remineralization supported by supersaturation with calcium, phosphate, and fluoride, and protective actions of salivary and acquired pellicle proteins.

Why it matters

Synthesizing the physiological mechanisms of salivary protection against acid wear helps inform the development of targeted therapies and preventive strategies for dental erosion.

Limits

The abstract does not report the number of included studies, specific inclusion criteria, or quantitative metrics. As a narrative synthesis of biological mechanisms, it does not evaluate the clinical efficacy of specific interventions.

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