Brito · European journal of preventive cardiology 2014 · retrospective cohort study · n=2002

Ability to sit and rise from the floor as a predictor of all-cause mortality.

Cited 167 times in the scientific literature.

Level 3 - non-randomized controlled study

Retrospective cohort follow-up study

PubMed 23242910 · doi:10.1177/2047487312471759 · record verified 2026-08-29

What was done

A retrospective cohort study evaluated 2,002 adults aged 51–80 years (68% men) who performed a sitting-rising test (SRT) to and from the floor. Sitting and rising were each scored from 0 to 5, subtracting one point for each support used (hand or knee), yielding a composite score from 0 to 10. Participants were stratified into four categories: 0–3, 3.5–5.5, 6–7.5, and 8–10. All-cause mortality was tracked over a median follow-up of 6.3 years.

What was found

Over median follow-up, 159 deaths (7.9%) occurred. Lower SRT scores were associated with higher mortality (p < 0.001). Adjusted for age, sex, and body mass index, hazard ratios for mortality compared to the highest category (8–10) were 5.44 (95% CI 3.1–9.5) for scores 0–3, 3.44 (95% CI 2.0–5.9) for scores 3.5–5.5, and 1.84 (95% CI 1.1–3.0) for scores 6–7.5 (p < 0.001). Each 1-unit increase in SRT score was associated with a 21% improvement in survival.

Why it matters

The sitting-rising test provides a simple, non-invasive, and equipment-free functional assessment of musculoskeletal fitness that strongly predicts all-cause mortality in middle-aged and older adults.

Limits

The study was retrospective and observational, meaning causality cannot be established. Adjustment was limited to age, sex, and BMI in the reported model; major potential confounders such as smoking status, cardiorespiratory fitness, baseline chronic diseases, and medications were not reported in the abstract. The cohort was predominantly male (68%).

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