Bellofiore · Annals of biomedical engineering 2013 · narrative review · n=?

Methods for measuring right ventricular function and hemodynamic coupling with the pulmonary vasculature.

Cited 97 times in the scientific literature.

Level 5 - mechanism / opinion, no new human data

Narrative review of physiological mechanics and measurement techniques without systematic methodology or original data.

PubMed 23423705 · doi:10.1007/s10439-013-0752-3 · record verified 2026-08-27

What was done

This narrative review summarizes right ventricular (RV) physiology and biomechanics, along with established and novel invasive and non-invasive methods for assessing RV function and RV-pulmonary vascular hemodynamic coupling, particularly in the context of pulmonary hypertension.

What was found

The abstract reports no numerical findings or statistical data. It notes that because the RV and compliant pulmonary circulation differ structurally and functionally from the left ventricle and systemic circulation, left ventricular metrics cannot be directly applied without modification to evaluate RV function and coupling.

Why it matters

Understanding RV-pulmonary vascular coupling is critical for managing conditions like pulmonary hypertension, and developing non-invasive metrics enables better monitoring of disease progression and therapeutic response.

Limits

The paper is a non-systematic narrative review providing no primary experimental data or statistical analyses. The abstract does not report comparative diagnostic accuracy, reproducibility, or clinical validation metrics for the reviewed measurement techniques.

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