The brain's default network: origins and implications for the study of psychosis.
Level 5 - mechanism / opinion, no new human data
Narrative review and theoretical framework without empirical data or systematic search
PubMed 24174906 · doi:10.31887/DCNS.2013.15.3/rbuckner
What was done
This narrative review synthesizes literature on the functional role of the brain's default network in passive states and directed mental simulation tasks, examining the hypothesis that default network disruption contributes to psychosis.
What was found
The abstract reports no quantitative data or numerical outcomes. It reports conceptually that the default network facilitates the construction of mental models and that psychosis may represent a network disturbance driven by dysfunctional interactions between frontoparietal control systems and the default network.
Why it matters
It provides a conceptual framework linking disordered thought in psychosis to imbalances across large-scale competitive brain networks rather than isolated regional deficits.
Limits
This is a narrative review presenting no new primary data or systematic review methodology. The abstract notes that functional imaging of the default network in patient populations is heavily confounded by head motion and compliance issues.
Cited by
- supports The default mode network of the brain is activated during quiet rest, mind-wandering, and internally directed reflection rather than active external sensory or task processing.