Role of the gut microbiota in human nutrition and metabolism.
Level 5 - mechanism / opinion, no new human data
Narrative review without systematic search methodology or new empirical data
PubMed 24251697 · doi:10.1111/jgh.12294
What was done
This is a narrative review summarizing the metabolic interactions between commensal gut microbiota and the human host, focusing on molecular profiling advances, nutrient generation, and metabolic disease pathways.
What was found
The abstract provides no quantitative data or numerical findings. It qualitatively reports that gut microbiota produce short-chain fatty acids, B vitamins, and vitamin K, and interact with host epithelial and subepithelial receptors to modulate pathways implicated in metabolic syndrome, diabetes, non-alcoholic fatty liver disease, and cognition.
Why it matters
It outlines the expanded understanding of the gut microbiome from simple nutrient salvage to active regulation of host metabolism and chronic disease mechanisms.
Limits
As presented in the abstract, there are no primary clinical or experimental data, no numerical effect estimates, and no systematic review methodology.
Cited by
- partial All eight B vitamins are synthesized by human intestinal bacteria and can be absorbed by the host.