Umnov · Advances in gerontology = Uspekhi gerontologii 2013 · narrative review · n=?

[Neuroprotective effects of peptides bioregulators in people of various age].

Cited 8 times in the scientific literature.

Level 5 - mechanism / opinion, no new human data

Narrative review without systematic search methodology or primary data

PubMed 24738258 · record verified 2026-08-26

What was done

This review outlines the comparative characteristics of two groups of neuroprotective peptides: polypeptide complexes (cortexin, cerebrolysin) and short peptides (semax, cortagen, pinealon). It compiles cellular and molecular mechanisms of action alongside described clinical applications in elderly and old age populations based on the existing literature.

What was found

The abstract reports no numbers, effect sizes, or quantitative findings, stating only that comparative characteristics, clinical application data, and cellular mechanisms are described.

Why it matters

It organizes the classification and reported mechanisms of peptide bioregulators evaluated for neuroprotection across different age cohorts.

Limits

The abstract provides no sample sizes, primary trial methodologies, control conditions, or numerical results. As a narrative review, it lacks a systematic literature search and formal quality assessment.

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