· Pediatrics 2014 · narrative review · n=?

Iodine deficiency, pollutant chemicals, and the thyroid: new information on an old problem.

Cited 96 times in the scientific literature.

Level 5 - mechanism / opinion, no new human data

Narrative review and clinical/policy commentary without systematic review methodology

PubMed 24864180 · doi:10.1542/peds.2014-0900 · record verified 2026-08-29

What was done

This narrative review and clinical commentary summarizes evidence on iodine deficiency among US women of reproductive age, the compounding risks posed by environmental thyroid-disrupting pollutants (nitrate, thiocyanate, and perchlorate), current supplement utilization rates, and organizational guidelines.

What was found

The review reports that marginal iodine deficiency is common among US reproductive-age women, increasing susceptibility to environmental thyroid-disrupting chemicals. Only about 15% of pregnant and lactating women take iodide supplements, and commercially available supplements may contain inadequate iodide or carry inaccurate labeling. No other numerical outcomes or effect sizes are provided in the abstract.

Why it matters

It emphasizes that maternal iodine insufficiency is an ongoing public health concern exacerbated by chemical exposures and call for stronger regulatory oversight of supplement labeling and drinking water standards.

Limits

The abstract describes a narrative review and policy overview without systematic review methodology, meta-analysis, or primary clinical data. Specific effect sizes, exposure thresholds, and study characteristics are not detailed.

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