Role of magnesium in cardiovascular diseases.
Level 5 - mechanism / opinion, no new human data
Narrative review describing biological mechanisms without systematic review methodology
PubMed 24896250 · doi:10.1097/CRD.0000000000000003
What was done
This narrative review synthesizes the physiological, biochemical, and cellular mechanisms of magnesium in cardiovascular regulation, focusing on hypertension, atherosclerosis, coronary artery disease, congestive heart failure, and arrhythmias.
What was found
The abstract reports no numerical data or quantitative outcomes. It describes magnesium as playing a critical regulatory role in vascular smooth muscle tone, endothelial cell function, and myocardial excitability through vasodilatory, anti-inflammatory, anti-ischemic, and antiarrhythmic properties.
Why it matters
It highlights the mechanistic foundation for the biological relevance of magnesium across several major cardiovascular disease pathways.
Limits
The paper is a narrative review presenting no original empirical data, sample size, or systematic methodology. Quantitative clinical effect sizes are not reported.
Cited by
- supports Magnesium functions as a vasodilator to increase blood flow.