Zaura · Caries research 2015 · narrative review · n=?

Towards understanding oral health.

Cited 54 times in the scientific literature.

Level 5 - mechanism / opinion, no new human data

Narrative review and conceptual framework paper with no new empirical data

PubMed 25871419 · doi:10.1159/000377733 · record verified 2026-08-31

What was done

This narrative review applied the general health concept of allostasis (the capacity to adapt to physiological changes) to the oral ecosystem. The authors illustrated the multidimensionality of host and environmental factors involved in maintaining oral stability across the lifespan using physiological changes during puberty as an example.

What was found

The abstract reports no numerical data or empirical findings. It conceptually outlines that individual components of the oral cavity (such as hard tissues, the microbiome, saliva, and host immune response) have largely been studied in isolation, and argues that understanding oral health requires evaluating multidimensional interactions within a systems approach.

Why it matters

It proposes a shift in dental research from a disease-centric, static definition of oral health toward a dynamic, systems-level model of physiological adaptation across life stages.

Limits

The paper is a theoretical narrative overview presenting no original empirical measurements, systematic methodology, or quantitative data. Translating this systems framework into actionable clinical metrics faces substantial practical and resource challenges.

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