Shukitt-Hale · The British journal of nutrition 2015 · Controlled animal experiment · n=?

The beneficial effects of berries on cognition, motor behaviour and neuronal function in ageing.

Cited 109 times in the scientific literature.

Level 5 - mechanism / opinion, no new human data

Animal research

PubMed 26392037 · doi:10.1017/S0007114515003451 · record verified 2026-08-26

What was done

Aged Fischer 344 rats were fed either a control diet, a 2% strawberry-supplemented diet, or a 2% blueberry-supplemented diet for 8 weeks. Researchers assessed motor performance, cognitive behavior (specifically working memory), hippocampal neurogenesis, and expression of insulin-like growth factor 1 (IGF-1).

What was found

The abstract reports no numerical values, effect sizes, or statistical metrics. Qualitatively, rats fed either berry diet showed enhanced motor performance, improved working memory, increased hippocampal neurogenesis, and elevated IGF-1 expression compared to controls. The authors noted that the neurogenesis and IGF-1 increases could not solely explain the cognitive improvements.

Why it matters

This study provides preclinical evidence in a rodent model linking dietary berry intake to cellular neuroplastic markers and functional behavioral recovery in aging.

Limits

The study was conducted in aged rats and findings cannot be directly generalized to humans. The abstract omits sample sizes, exact rat ages, and all quantitative data or effect sizes.

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