Müri · The Journal of comparative neurology 2016 · narrative review · n=?

Cortical control of facial expression.

Cited 88 times in the scientific literature.

Level 5 - mechanism / opinion, no new human data

Narrative review synthesizing anatomical and functional motor control studies without systematic methodology.

PubMed 26418049 · doi:10.1002/cne.23908 · record verified 2026-08-28

What was done

Narrative review synthesizing findings from human and nonhuman primate studies on the cortical motor pathways underlying voluntary versus emotional facial expressions.

What was found

The abstract reports no quantitative data or statistical estimates. It outlines a distributed cortical network involving at least five regions per hemisphere: primary motor cortex, ventral lateral premotor cortex, supplementary motor area (medial wall), and rostral and caudal cingulate cortex. Innervation is bilaterally distributed for the upper face and predominantly contralateral for the lower face. Voluntary expression relies on the primary motor cortex, ventral lateral premotor cortex, and supplementary motor area, while emotional expression relies on rostral and caudal cingulate regions receiving limbic input.

Why it matters

Clarifies the anatomical separation between voluntary and emotionally driven motor pathways for facial movement, providing a framework for understanding facial paresis dissociations in clinical neurology.

Limits

As a narrative review, it lacks systematic search criteria, quality appraisal, and quantitative synthesis. Specific sample sizes, species-specific differences, and experimental paradigms are not reported in the abstract.

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