Vitamin D and benign gynaecological diseases: a critical analysis of the current evidence.
Level 5 - mechanism / opinion, no new human data
Narrative review of existing literature without systematic methodology
PubMed 26490176 · doi:10.3109/09513590.2015.1111329
What was done
This narrative review examined existing literature regarding the biological role of vitamin D metabolism in female reproductive tissues and its association with benign gynecological conditions, specifically endometriosis, uterine fibroids, and polycystic ovary syndrome (PCOS).
What was found
The abstract provides no quantitative data, effect sizes, or statistical metrics. It reports descriptively that vitamin D receptors are expressed in ovarian tissue, endometrium, fallopian epithelial cells, decidua, and placenta, and notes that literature suggests a link between vitamin D metabolism and the specified benign gynecological diseases.
Why it matters
It outlines the biological plausibility and clinical interest surrounding vitamin D signaling in common benign gynecological conditions.
Limits
The abstract describes a non-systematic narrative review with no defined search protocol, study selection criteria, or quality assessment. No primary patient data, sample sizes, or numerical findings are reported.
Cited by
- supports Vitamin D is a prohormone essential for sex and reproductive hormone production, inflammation reduction, and cognition.