den Harder · Clinical radiology 2016 · narrative review · n=?

New horizons in cardiac CT.

Cited 33 times in the scientific literature.

Level 5 - mechanism / opinion, no new human data

Narrative review of cardiac CT technologies without systematic methodology

PubMed 26932775 · doi:10.1016/j.crad.2016.01.022 · record verified 2026-08-30

What was done

This narrative review summarizes technological developments in cardiovascular computed tomography angiography (CCTA), covering dose-reduction techniques (tube current modulation, automatic tube potential selection, prospective ECG-triggering, and iterative reconstruction), CT-derived fractional flow reserve (FFR), dual-energy CT, and photon-counting CT.

What was found

Hardware and software optimizations reduce CCTA radiation exposure by approximately one order of magnitude, often to sub-millisievert dose levels. Computational advancements allow non-invasive measurement of fractional flow reserve from CCTA data. Dual-energy CT reduces beam hardening, aiding assessment in patients with high calcium burden and improving myocardial perfusion imaging. Photon-counting CT offers potential for further dose reduction, higher spatial resolution, and new contrast agents. The abstract provides no specific numerical diagnostic accuracy statistics or sample sizes.

Why it matters

It summarizes the transition of cardiac CT from a high-radiation anatomical scan to a low-dose, functional imaging modality capable of assessing hemodynamic significance and tissue properties.

Limits

This is a narrative review presenting no original empirical data, sample size, or systematic search methodology. Quantitative diagnostic performance metrics, clinical outcomes, costs, and availability constraints are not reported.

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