Hirose · Internal medicine (Tokyo, Japan) 2016 · case report · n=1

Concurrent Therapy with a Low-carbohydrate Diet and Miglitol Remarkably Improved the Postprandial Blood Glucose and Insulin Levels in a Patient with Reactive Hypoglycemia due to Late Dumping Syndrome.

Cited 14 times in the scientific literature.

Level 4 - case-series / case-control

Single clinical case report

PubMed 27150868 · doi:10.2169/internalmedicine.55.5655 · record verified 2026-08-29

What was done

This case report describes the clinical management of a single patient with reactive hypoglycemia secondary to late dumping syndrome following a total gastrectomy. The intervention consisted of concurrent therapy with an alpha-glucosidase inhibitor (miglitol) and a low-carbohydrate diet based on low-glycemic-index foods.

What was found

The abstract reports that the combined regimen effectively ameliorated postprandial fluctuations in blood glucose and plasma insulin levels. However, the abstract provides no specific numerical values, baseline metrics, or statistical measurements.

Why it matters

It highlights a combined dietary and pharmacological approach (miglitol plus a low-glycemic-index, low-carbohydrate diet) for managing reactive hypoglycemia secondary to late dumping syndrome.

Limits

This is an uncontrolled single-patient case report (n = 1), preventing causal confirmation or generalization. No quantitative glycemic or insulin values are reported in the abstract.

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