Vrcek · Journal of cutaneous and aesthetic surgery 2016 · narrative review · n=?

Infraorbital Dark Circles: A Review of the Pathogenesis, Evaluation and Treatment.

Cited 91 times in the scientific literature.

Level 5 - mechanism / opinion, no new human data

Narrative review incorporating expert opinion and clinical experience without systematic appraisal

PubMed 27398005 · doi:10.4103/0974-2077.184046 · record verified 2026-08-31

What was done

The authors conducted a narrative literature search across MEDLINE and non-MEDLINE databases using keywords related to infraorbital dark circles and lower eyelid bags. Findings from the literature were synthesized alongside clinical experience from the authors' own practice to discuss the etiology, pathogenesis, evaluation, and management of the condition.

What was found

The abstract reports no empirical data, sample sizes, or quantitative outcome measures. It outlines infraorbital dark circles as a multifactorial condition driven by deep facial anatomy, soft tissue alterations, and cutaneous factors, managed by approaches ranging from cosmeceuticals and makeup to lasers, chemical peels, soft-tissue fillers, fat transfer, and surgery.

Why it matters

This review outlines the anatomic and dermatologic contributors to periorbital dark circles to help clinicians match tailored interventions to specific etiologies.

Limits

The abstract describes a non-systematic narrative review combined with personal practice experience, with no reported search criteria, quality appraisal, or numerical outcome metrics.

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