Amlung · Addiction (Abingdon, England) 2017 · systematic review and meta-analysis · n=?

Steep delay discounting and addictive behavior: a meta-analysis of continuous associations.

Cited 625 times in the scientific literature.

Level 1 - systematic review of randomized trials

Systematic review and meta-analysis of observational studies (by design analogy, non-interventional)

PubMed 27450931 · doi:10.1111/add.13535 · record verified 2026-08-26

What was done

Meta-analysis of published peer-reviewed studies (identified via PubMed, MEDLINE, and PsycINFO) examining continuous associations between delayed reward discounting (DRD) of monetary gains and addictive behaviors (alcohol, tobacco, cannabis, stimulants, opiates, and gambling). Effect sizes were pooled using random-effects models (Pearson's r). Moderation analyses examined addiction severity versus quantity-frequency (QF), addictive behavior type, and DRD assessment modality. Publication bias was evaluated using fail-safe N, Begg-Mazumdar, Egger's tests, meta-regression, and study imputation.

What was found

The meta-analysis revealed a small, highly significant continuous association between steeper DRD and addictive behaviors (r = 0.14, P < 10^-14). Effect sizes were significantly larger for addiction severity measures compared with QF measures (P = 0.01). No significant differences were observed across addictive behavior categories (P = 0.30) or DRD assessment methods (P = 0.90). Publication bias indices indicated a modest impact of unpublished findings.

Why it matters

It demonstrates that delayed reward discounting is a consistent continuous correlate across diverse substance and behavioral addictions, linking more strongly to clinical severity than to quantity-frequency of use.

Limits

The abstract does not state the total number of included studies or participants. The underlying evidence is observational and cross-sectional, precluding causal inference. The analysis was restricted to monetary reward discounting and published literature.

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