Thyroid and shoulder diseases: the bases of a linked channel.
Level 5 - mechanism / opinion, no new human data
Narrative review of preclinical mechanisms, retrospective studies, and case reports
What was done
The authors performed a narrative review examining preclinical in vivo and in vitro models as well as retrospective studies and case reports on the relationship between thyroid hormone imbalance and shoulder pathologies.
What was found
The abstract reports no numerical data or effect sizes. It reports that basic science studies demonstrate thyroid hormone involvement in bone, cartilage, and tendon biology, and that retrospective studies and case reports suggest thyroid disorders serve as risk factors and prognostic indicators in shoulder pain conditions.
Why it matters
It highlights a possible systemic endocrine component in shoulder pathology and suggests clinicians consider screening for thyroid disorders in patients presenting with common shoulder conditions.
Limits
The abstract provides no sample sizes, numerical metrics, or systematic search methodology. The cited clinical evidence relies on retrospective designs and case reports, which cannot establish causality or determine clinical effect sizes.
Cited by
- partial Hypothyroidism is associated with and can present as frozen shoulder and tendon tears.