Mendez · The Journal of neuropsychiatry and clinical neurosciences 2017 · Case series · n=?

Psychotic-Like Speech in Frontotemporal Dementia.

Cited 14 times in the scientific literature.

Level 4 - case-series / case-control

Descriptive case series / observational subgroup report without reported controls.

PubMed 27707194 · doi:10.1176/appi.neuropsych.16030058 · record verified 2026-08-26

What was done

The authors identified and examined a subgroup of individuals with behavioral variant frontotemporal dementia (bvFTD) presenting with psychotic-like speech characteristics and evaluated their neuroanatomical patterns of brain atrophy.

What was found

The abstract reports no numerical data, effect sizes, or participant numbers. It notes that a subgroup of bvFTD patients exhibited psychotic-like speech phenomena—specifically pressure of speech, tangentiality, derailment, clanging/rhyming, and punning—in the absence of other psychotic features, which was associated with right anterior temporal atrophy and sparing of the left frontal lobe.

Why it matters

It highlights a distinct clinical phenotype in bvFTD where formal thought disorder-like speech occurs without overt psychosis, pointing to a possible right anterior temporal neuroanatomical basis.

Limits

The abstract provides no sample size, demographic details, inclusion criteria, statistical measures, or control group comparisons, precluding independent evaluation of the findings.

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