Ross · Circulation 2016 · narrative review / expert scientific statement · n=?

Importance of Assessing Cardiorespiratory Fitness in Clinical Practice: A Case for Fitness as a Clinical Vital Sign: A Scientific Statement From the American Heart Association.

Cited 2471 times in the scientific literature.

Level 5 - mechanism / opinion, no new human data

Narrative scientific statement and expert review without a systematic review methodology or new human data.

PubMed 27881567 · doi:10.1161/CIR.0000000000000461 · record verified 2026-08-26

What was done

This American Heart Association scientific statement reviewed epidemiological and clinical evidence regarding the association between cardiorespiratory fitness (CRF) and major health outcomes, focusing on its potential utility in clinical risk prediction, risk reclassification, and patient management.

What was found

No quantitative effect sizes, hazard ratios, or participant numbers are reported in the abstract. Qualitatively, low CRF is reported to be associated with increased risk of cardiovascular disease, cancer mortality, and all-cause mortality. The statement notes CRF is potentially a stronger predictor of mortality than smoking, hypertension, dyslipidemia, and type 2 diabetes, and improves risk reclassification when added to traditional risk factors.

Why it matters

The statement makes the clinical case for treating cardiorespiratory fitness as a standard vital sign to enhance risk stratification and guide lifestyle-based preventive interventions.

Limits

This is a non-systematic narrative scientific statement and expert consensus rather than an empirical trial or systematic review. The abstract provides no quantitative data, search criteria, study counts, or specific protocols for implementing fitness assessments in routine clinical workflows.

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