Curthoys · Experimental brain research 2017 · narrative review · n=?

The new vestibular stimuli: sound and vibration-anatomical, physiological and clinical evidence.

Cited 115 times in the scientific literature.

Level 5 - mechanism / opinion, no new human data

Narrative review of anatomical and physiological mechanisms without systematic search methodology

PubMed 28130556 · doi:10.1007/s00221-017-4874-y · record verified 2026-08-26

What was done

This paper reviews anatomical and physiological evidence regarding the spatial and mechanical differentiation of otolith maculae, focusing on receptor types, hair bundle stiffness, attachment to the otolithic membrane, and afferent neural responses to sound and vibration stimuli.

What was found

The striola contains predominantly type I receptors with short, stiff hair bundles that project into holes in the otolithic membrane with looser attachment than extrastriolar receptors. Fluid displacement from sound or vibration deflects these hair bundles, activating irregular afferents that exhibit phase-locking to stimulus cycles at frequencies above 2000 Hz. The abstract reports no other quantitative metrics.

Why it matters

It provides the biophysical and physiological rationale supporting the application of sound and vibration stimuli in clinical tests of vestibular function.

Limits

As a narrative review, it lacks a systematic search methodology, quality assessment, and quantitative synthesis. The abstract provides no sample sizes, clinical diagnostic accuracy figures, or human trial data.

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