Meng · Nutrients 2017 · narrative review · n=?

Dietary Sources and Bioactivities of Melatonin.

Cited 360 times in the scientific literature.

Level 5 - mechanism / opinion, no new human data

Narrative review synthesizing food sources and mechanisms without systematic review methodology.

PubMed 28387721 · doi:10.3390/nu9040367 · record verified 2026-08-29

What was done

A narrative review summarizing literature on dietary sources of melatonin (across fungi, plants, and animals), changes in human serum melatonin concentrations following consumption of melatonin-containing foods, and melatonin's documented biological activities and mechanisms.

What was found

The abstract reports no numerical values or effect sizes. It notes that eggs and fish are the highest animal-derived sources, nuts have the highest content among plant foods, and mushrooms, cereals, and germinated legumes or seeds are also good sources. The review notes that dietary intake can significantly increase human serum melatonin concentrations and lists diverse bioactivities including antioxidant, anti-inflammatory, immune-boosting, anticancer, cardiovascular-protective, anti-diabetic, anti-obesity, neuroprotective, and anti-aging properties.

Why it matters

It catalogues natural dietary sources of melatonin that may contribute to circulating melatonin levels and influence sleep and overall health.

Limits

The abstract provides no quantitative data on food melatonin concentrations, bioavailability, or clinical outcome effect sizes. As a narrative review, it lacks systematic search criteria, quality appraisal of included studies, and control for potential publication bias.

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