Grgic · PeerJ 2017 · systematic review and meta-analysis · n=13 studies

Effects of linear and daily undulating periodized resistance training programs on measures of muscle hypertrophy: a systematic review and meta-analysis.

Cited 42 times in the scientific literature.

Level 1 - systematic review of randomized trials

Systematic review and meta-analysis of intervention trials

PubMed 28848690 · doi:10.7717/peerj.3695 · record verified 2026-08-27

What was done

The authors conducted a systematic review and meta-analysis of intervention trials comparing the effects of linear periodization (LP) versus daily undulating periodization (DUP) resistance training programs on muscle hypertrophy. Searches were performed across PubMed/MEDLINE, Scopus, Web of Science, SPORTDiscus, NDLTD, and OATD.

What was found

Across 13 eligible studies, the pooled standardized mean difference (Cohen's d) between LP and DUP for muscle hypertrophy was -0.02 (95% CI [-0.25, 0.21], p = 0.848).

Why it matters

Linear and daily undulating periodization models appear to yield equivalent hypertrophic gains, offering programming flexibility.

Limits

The abstract does not report the total participant sample size. The authors note the need for further research in trained and clinical populations and recommend future use of more sensitive imaging modalities like ultrasound or MRI.

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