Kunutsor · Annals of medicine 2018 · prospective cohort study · n=2277

Joint associations of sauna bathing and cardiorespiratory fitness on cardiovascular and all-cause mortality risk: a long-term prospective cohort study.

Cited 57 times in the scientific literature.

Level 3 - non-randomized controlled study

Prospective observational cohort study

PubMed 28972808 · doi:10.1080/07853890.2017.1387927 · record verified 2026-08-29

What was done

A prospective cohort study assessed baseline cardiorespiratory fitness (CRF, measured via respiratory gas analysis) and frequency of sauna bathing (FSB) in 2,277 men. CRF was categorized as low or high by median split, and FSB was categorized as low (≤2 sessions/week) or high (3-7 sessions/week). Participants were followed for a median of 26.1 years to track cardiovascular and all-cause mortality.

What was found

During follow-up, 520 cardiovascular deaths and 1,124 all-cause deaths occurred. Comparing high versus low CRF, multivariate-adjusted hazard ratios (HRs) were 0.51 (95% CI, 0.41-0.63) for cardiovascular mortality and 0.65 (95% CI, 0.57-0.75) for all-cause mortality. For high versus low FSB, HRs were 0.74 (95% CI, 0.59-0.94) for cardiovascular mortality and 0.84 (95% CI, 0.72-0.97) for all-cause mortality. Compared with the low CRF & low FSB reference group, HRs for cardiovascular mortality were 0.42 (95% CI, 0.28-0.62) for high CRF & high FSB, 0.50 (95% CI, 0.39-0.63) for high CRF & low FSB, and 0.72 (95% CI, 0.54-0.97) for low CRF & high FSB. Corresponding HRs for all-cause mortality were 0.60 (95% CI, 0.48-0.76), 0.63 (95% CI, 0.54-0.74), and 0.78 (95% CI, 0.64-0.96).

Why it matters

Frequent sauna bathing and cardiorespiratory fitness show additive associations with reduced mortality risk, suggesting separate and complementary pathways of cardiovascular protection.

Limits

The cohort included only men, limiting generalizability to women. Sauna use and fitness were measured only at baseline without accounting for changes over the 26.1-year median follow-up. As an observational study, residual confounding from socioeconomic status or overall healthy behaviors cannot be ruled out.

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