Holick · Advances in experimental medicine and biology 2017 · narrative review · n=?

Ultraviolet B Radiation: The Vitamin D Connection.

Cited 73 times in the scientific literature.

Level 5 - mechanism / opinion, no new human data

Narrative review / book chapter detailing biological mechanisms without systematic search methodology or new empirical data.

PubMed 29124697 · doi:10.1007/978-3-319-56017-5_12 · record verified 2026-08-26

What was done

This chapter provides a narrative review detailing how skin exposure to solar ultraviolet B converts 7-dehydrocholesterol into vitamin D3, the evolutionary significance of this pathway in vertebrates, variables influencing cutaneous synthesis, and guidance on sensible sun exposure.

What was found

The abstract reports purely qualitative overviews of synthesis pathways and biologic functions; no numerical data, sample sizes, or effect estimates are provided.

Why it matters

It outlines the basic physiological mechanisms linking sunlight exposure to vitamin D production and systemic health.

Limits

The abstract provides no primary data, systematic search criteria, or quantitative results. As an expert narrative review, it offers mechanistic background rather than empirical outcome testing.

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