Lactoferrin: Major Physiological Functions and Applications.
Level 5 - mechanism / opinion, no new human data
Narrative review summarizing biological mechanisms and applications without systematic methodology
PubMed 29756573 · doi:10.2174/1389203719666180514150921
What was done
This narrative review synthesized literature on the distribution, physiological mechanisms, biological functions, and commercial or clinical applications of lactoferrin (lactotransferrin).
What was found
The abstract reports that lactoferrin regulates intestinal iron absorption, directly or indirectly chelates iron, exhibits antimicrobial, antiviral, antioxidant, anti-cancer, and anti-inflammatory activities, and serves as an adjuvant in intestinal diseases and infant formula. The abstract provides no quantitative data or numerical outcomes.
Why it matters
It outlines the multifaceted physiological actions of lactoferrin, highlighting its relevance to infant nutrition, iron regulation, and disease adjuvant therapies.
Limits
The paper is a non-systematic narrative overview with no described search criteria, quality appraisal, or quantitative synthesis. Abstract-reported benefits rely on descriptive claims without specific clinical trial metrics, effect sizes, or safety data.
Cited by
- supports Lactoferrin binds iron in the gastrointestinal tract and facilitates its absorption into the body.