Hooper · The Physician and sportsmedicine 2018 · narrative review · n=?

Treating exercise-associated low testosterone and its related symptoms.

Level 5 - mechanism / opinion, no new human data

Narrative review and expert opinion without systematic review methodology or new human data

PubMed 30063407 · doi:10.1080/00913847.2018.1507234 · record verified 2026-08-26

What was done

This narrative review describes the Exercise-Hypogonadal Male Condition (EHMC), its occurrence across endurance, anaerobic, power, and weight-class sports, and non-pharmacological treatment approaches for athletes subject to anti-doping regulations.

What was found

The abstract reports no numerical data. It notes that high exercise volumes can lower testosterone levels and cause symptoms such as fatigue, sexual dysfunction, and low bone mineral density. Because pharmacological options like testosterone or clomiphene citrate are banned by the World Anti-Doping Agency, the authors recommend managing EHMC through nutritional intervention and training modification.

Why it matters

It highlights exercise-induced hypogonadism across diverse athletic disciplines and emphasizes non-pharmacological management compliant with anti-doping rules.

Limits

This is a narrative review providing expert recommendations with no original empirical data, quantitative synthesis, or detailed intervention protocols reported in the abstract.

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