Neven · Seminars in reproductive medicine 2018 · narrative review · n=?

A Summary on Polycystic Ovary Syndrome: Diagnostic Criteria, Prevalence, Clinical Manifestations, and Management According to the Latest International Guidelines.

Cited 197 times in the scientific literature.

Level 5 - mechanism / opinion, no new human data

Narrative review summarizing international guideline recommendations and clinical features without original data or systematic review methodology

PubMed 30189445 · doi:10.1055/s-0038-1668085 · record verified 2026-08-26

What was done

The authors synthesized key clinical features of polycystic ovary syndrome (PCOS) to introduce an issue on the international evidence-based guideline for PCOS assessment and management. The review covered diagnostic criteria (specifically the Rotterdam criteria and associated phenotypes), prevalence, clinical manifestations across reproductive, metabolic, and psychological domains, and management strategies ranging from lifestyle interventions to reproductive and nonreproductive treatments.

What was found

The abstract provides a conceptual overview rather than quantitative data. It notes that the Rotterdam criteria are now internationally accepted for identifying diverse PCOS phenotypes, that the condition remains underdiagnosed with significant diagnostic delays, and that evidence-based management requires lifestyle and medical strategies targeting reproductive, metabolic, and psychological sequelae. No numerical values or effect sizes were reported in the abstract.

Why it matters

It provides a high-level summary of the international consensus guidelines for PCOS, emphasizing the necessity of multidisciplinary screening and early intervention for a complex disorder with high rates of delayed diagnosis.

Limits

The abstract reports no primary data, systematic search methodology, or quantitative outcomes. As a narrative review, it reflects broad guideline summaries rather than verifiable empirical comparisons.

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