Harlow · Obstetrics and gynecology clinics of North America 2018 · narrative review · n=?

Menstrual Cycle Changes as Women Approach the Final Menses: What Matters?

Cited 21 times in the scientific literature.

Level 5 - mechanism / opinion, no new human data

Narrative review describing STRAW+10 bleeding criteria without systematic search or meta-analytic data.

PubMed 30401545 · doi:10.1016/j.ogc.2018.07.003 · record verified 2026-08-29

What was done

This review examined menstrual cycle alterations occurring during the approach to the final menstrual period. It describes the application of the STRAW+10 bleeding criteria for identifying the onset of the early and late menopausal transition, variations in individual bleeding experiences, and patterns of ovulatory function and bleeding abnormalities.

What was found

The abstract provides no quantitative data or specific numerical estimates. It reports that cycle length variability and long cycles increase as menopause nears, episodes of excessive and prolonged bleeding carry a high probability, and ovulation continues to occur as women approach the final menstrual period.

Why it matters

It outlines the clinical bleeding markers of the menopausal transition according to established staging frameworks (STRAW+10), highlighting that both heavy bleeding episodes and ovulation remain common before final menses.

Limits

As a narrative review, it does not detail systematic search methods, study quality ratings, or meta-analytic data. No specific sample sizes, demographic details, or exact statistical frequencies are reported in the abstract.

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