Regulation of adult hippocampal neurogenesis exerted by sexual, cognitive and physical activity: An update.
Level 5 - mechanism / opinion, no new human data
Narrative review without systematic search or primary human data reported in the abstract
PubMed 31421204 · doi:10.1016/j.jchemneu.2019.101667
What was done
The authors conducted a narrative review summarizing the literature on adult hippocampal neurogenesis, focusing on how environmental and behavioral factors—specifically physical exercise, cognitive engagement, and sexual activity—influence the generation of new neurons and their integration into brain circuitry.
What was found
No numerical data, effect sizes, or specific metrics are reported in the abstract. The review describes adult hippocampal neurogenesis as a life-long process responsive to environmental modulation, specifically regulated by physical, cognitive, and sexual activities.
Why it matters
Synthesizing non-pharmacological modulators of neurogenesis clarifies potential behavioral pathways for supporting hippocampal plasticity, memory storage, and resilience against neurodegeneration.
Limits
This is a narrative review providing no systematic methodology, study count, or sample sizes. The abstract does not specify the balance between animal and human evidence, nor does it provide quantitative thresholds or effect sizes for the reported behavioral interventions.
Cited by
- supports Every human grows new brain cells every day through neurogenesis, a process promoted by aerobic exercise.