Speakman · Annals of nutrition & metabolism 2019 · Database description / registry report · n=6,621

The International Atomic Energy Agency International Doubly Labelled Water Database: Aims, Scope and Procedures.

Cited 47 times in the scientific literature.

Level 5 - mechanism / opinion, no new human data

Database description and methodology report without comparative empirical analysis

PubMed 31743893 · doi:10.1159/000503668 · record verified 2026-08-30

What was done

This paper describes the aims, scope, and procedures of the International Atomic Energy Agency (IAEA) Doubly Labelled Water (DLW) Database, established to pool individual participant total energy expenditure (TEE) data across worldwide laboratories.

What was found

The database aggregates 6,621 measurements of TEE obtained via the DLW method from individuals across 23 countries, along with accompanying participant characteristics. No empirical findings or statistical analyses are reported in the abstract.

Why it matters

Because DLW is costly and individual studies are typically underpowered, pooling international data allows researchers to investigate large-scale questions regarding how human energy expenditure varies by age, sex, environment, and temporal trends.

Limits

The paper serves as a database description rather than an empirical study, providing no analytical findings or effect sizes in the abstract. Pooled data from separate historical studies are inherently subject to between-study heterogeneity and geographic sampling disparities.

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