Lyons · Nutrients 2020 · narrative review · n=?

Breast Milk, a Source of Beneficial Microbes and Associated Benefits for Infant Health.

Cited 614 times in the scientific literature.

Level 5 - mechanism / opinion, no new human data

Narrative review without systematic search methodology

PubMed 32283875 · doi:10.3390/nu12041039 · record verified 2026-08-29

What was done

This narrative review synthesizes published literature on mammary gland development during lactation, the composition and potential sources of the human breast milk microbiome (specifically the entero-mammary transfer pathway), and the isolation of milk-derived bacterial strains for use as infant probiotics.

What was found

The abstract presents no quantitative data or numerical outcomes. It reports qualitative concepts: breast milk contains a distinct, non-contaminant microbiome that helps prevent pathogen adhesion and supports beneficial infant gut colonization, with maternal gut-to-mammary transfer serving as a proposed origin mechanism for these commensal bacteria.

Why it matters

Synthesizes the biological understanding of breast milk as an active source of commensal microbes rather than a sterile fluid, supporting the exploration of milk-derived bacterial strains as potential probiotics for infant nutrition.

Limits

As a narrative review, it does not employ systematic review methods, predefined study selection criteria, or quantitative meta-analyses. The abstract provides no specific sample sizes, strain-specific effect sizes, or comparative clinical trial data.

Cited by