Su-Velez · JAMA otolaryngology-- head & neck surgery 2020 · narrative review · n=?

Decontamination Methods for Reuse of Filtering Facepiece Respirators.

Cited 23 times in the scientific literature.

Level 5 - mechanism / opinion, no new human data

Narrative review of bench research and expert consensus without systematic review methodology

PubMed 32614377 · doi:10.1001/jamaoto.2020.1423 · record verified 2026-08-29

What was done

Narrative review synthesizing evidence on decontamination and sterilization methods for filtering facepiece respirators (N95s) during PPE shortages, evaluating their effects on material integrity, filtration efficacy, and respirator fit, alongside protocols for respirator rotation.

What was found

The abstract reports no quantitative numerical data. Qualitatively, decontamination using soap and water, alcohols, bleach, microwave heat, or high dry heat degrades respirator materials and renders them nonfunctional. In contrast, UV light, steam, low dry heat, ethylene oxide, and vaporized hydrogen peroxide appear viable for decontamination without destroying filtration or fit. Rotating respirators with a 72-hour rest interval to allow natural time decontamination is also reported as a viable strategy.

Why it matters

Provides guidance to healthcare institutions facing critical PPE shortages on which decontamination techniques preserve respirator function and which common disinfection methods destroy protective filtration.

Limits

The abstract describes a narrative review without reported systematic search methods, study counts, or specific quantitative outcomes on filtration efficiency or maximum safe reuse cycles. No clinical trial or infection prevention outcome data in human healthcare workers are presented.

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