Novel Use of Feminization Laryngoplasty.
Level 4 - case-series / case-control
Single patient case report
PubMed 33500201 · doi:10.1016/j.jvoice.2020.12.048
What was done
A case report was conducted on a single young female patient who developed severe, irreversible vocal virilization (androphonia) and reduced quality of life secondary to a testosterone-producing adrenocortical adenoma. Following inadequate response to etiology management and vocal therapy, she underwent voice feminization surgery via Wendler glottoplasty.
What was found
The abstract reports that the patient had a preoperative fundamental frequency lower than that of an average adolescent male. Following Wendler glottoplasty, significant improvements in fundamental frequency, self-esteem, and quality of life were reported. The abstract provides no exact numerical values or acoustic measurements.
Why it matters
This report describes a novel clinical application of Wendler glottoplasty, demonstrating that surgical voice feminization techniques can be utilized in non-transgender women with severe, refractory androphonia caused by endocrine disorders.
Limits
The report is an uncontrolled single-patient case study (n = 1). The abstract reports no numerical acoustic data (such as fundamental frequency in Hz), validated quality-of-life score changes, surgical complication details, or follow-up duration.
Cited by
- supports Voice deepening in women caused by androgen/testosterone virilization is irreversible.