Adherence to Ketogenic and Mediterranean Study Diets in a Crossover Trial: The Keto-Med Randomized Trial.
Level 2 - randomized trial
Secondary analysis of an individual randomized crossover trial
PubMed 33802709 · doi:10.3390/nu13030967
What was done
Secondary analysis of the Keto-Med randomized crossover trial comparing adherence to a Well Formulated Ketogenic Diet (WFKD) versus a Mediterranean Plus diet (Med-Plus). Adherence was assessed using study-specific scores at six time points: baseline, week 4 of each phase (food delivered), week 12 of each phase (food self-provided), and 12 weeks post-intervention when participants chose their own diets.
What was found
The abstract reports no numerical values or statistical comparisons. It reports qualitatively that average adherence to both diet patterns was very similar during the intervention phases, with a wide range of individual adherence observed across both diet types and during both delivery and self-provided periods.
Why it matters
Understanding how well participants follow ketogenic versus Mediterranean diets under controlled delivery versus real-world grocery purchasing informs the interpretation and design of future nutritional trials.
Limits
The abstract does not state the sample size, participant demographics, completion rates, or numerical adherence metrics. The adherence score was study-specific rather than an externally validated instrument, and post-intervention follow-up outcomes are not described.
Cited by
- supports In the Keto-Med crossover trial comparing a ketogenic diet to a Mediterranean diet over 24 weeks with a 12-week free-choice follow-up, participants consistently shifted toward the Mediterranean diet pattern during the free-choice period.